Professor Dr. Akram Shah received his PhD in Parasitology from King’s college London in 1993. After completion of PhD he joined University of Peshawar (Pakistan) as Lecturer in 1994 and was promoted
to the position of Professor in 2009. He completed several post-doctoral fellowships (2002-2003 S&T (HEC) Post-Doc, 2006 Commonwealth Post-Doc, 2009 Journal of Cell Science
Cambridge Post-Doc, 2011-2015 INSPIRE British Council Post-Doc Research 45-60 days in each year) from King’s College London & London School of Hygiene & Tropical Medicine.
Professor Shah won S&T Doctoral (1988-92) & Post-doctoral (2002-2003) awards by Govt. of Pakistan, Commonwealth Fellowship.
My major research focus is on understanding intra-macrophage survival and other molecular mechanisms involved in antileishmanial
drugs related apoptosis and survival of Leishmania tropica causing a disease called cutaneous Leishmaniasis (CL) which affects people
in 91 countries of the old world (including Pakistan) and new world with a global prevalence of 15 million cases. CL is reported from all
the provinces and all the major cities of Pakistan. The most promising oral drug today is miltefosine, so currently we are exploring immunomodulation
and the action of this drug along with Buparvaquone in CL infected THP-1 cells along with all the molecular events related to apoptosis in these cells.
The re-emergence and rapid spread of leishmaniasis is beyond doubt. During the past few years the global scenario regarding the epidemiology of Leishmaniasis
has changed. In concert with increase in prevalence and high rate of incidence and limitations on the part of currently available therapies, it has become an
extreme exigency to search new drugs for the disease.
Present Address: Head Life and Chemical Sciences & Professor of Zoology, Qurtuba University of Science & Information Technology Phase 3 Hayatabad, Peshawar, Pakistan.
Former: Professor & Chairman, Department of Zoology, University of Peshawar Pakistan.
Email: [email protected],
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